Publications of Winfried Denk

Kornfeld, J.; Januszewski, M.; Schubert, P. J.; Jain, V.; Denk, W.; Fee, M. S.: An anatomical substrate of credit assignment in reinforcement learning. bioRxiv: the preprint server for biology (2025)

Abbott, L. F.; Bock, D. D.; Callaway, E. M.; Denk, W.; Dulac, C.; Fairhall, A. L.; Fiete, I.; Harris, K. M.; Helmstaedter, M.; Jain, V. et al.; Kasthuri, N.; LeCun, Y.; Lichtman, J. W.; Littlewood, P. B.; Luo, L.; Maunsell, J. H. R.; Reid, R. C.; Rosen, B. R.; Rubin, G. M.; Sejnowski, T. J.; Seung, H. S.; Svoboda, K.; Tank, D. W.; Tsao, D.; Van Essen, D. C.: The mind of a mouse. Cell 182 (6), pp. 1372 - 1376 (2020)

Boergens, K. M.; Kapfer, C.; Helmstaedter, M.; Denk, W.; Borst, A.: Full reconstruction of large lobula plate tangential cells in Drosophila from a 3D EM dataset. PLoS One 13 (11), e0207828 (2018)

Svara, F. N.; Kornfeld, J.; Denk, W.; Bollmann, J. H.: Volume EM reconstruction of spinal cord reveals wiring specificity in speed-related motor circuits. Cell Reports 23 (10), pp. 2942 - 2954 (2018)

Kornfeld, J.; Denk, W.: Progress and remaining challenges in high-throughput volume electron microscopy. Current Opinion in Neurobiology 50, pp. 261 - 267 (2018)

Januszewski, M.; Kornfeld, J.; Li, P. H.; Pope, A.; Blakely, T.; Lindsey, L.; Maitin-Shepard, J.; Tyka, M.; Denk, W.; Jain, V.: High-precision automated reconstruction of neurons with flood-filling networks. Nature Methods 15 (8), pp. 605 - 610 (2018)

Rickgauer, J. P.; Grigorieff, N.; Denk, W.: Single-protein detection in crowded molecular environments in cryo-EM images. eLife 6, e25648 (2017)

Kornfeld, J.; Benezra, S. E.; Narayanan, R. T.; Svara, F. N.; Egger, R.; Oberlaender, M.; Denk, W.; Long, M. A.: EM connectomics reveals axonal target variation in a sequence-generating network. eLife 6, e24364 (2017)

Mikula, S.; Denk, W.: High-resolution whole-brain staining for electron microscopic circuit reconstruction. Nature Methods 12 (6), pp. 541 - 546 (2015)

Kim, J. S.; Greene, M. J.; Zlateski, A.; Lee, K.; Richardson, M.; Turaga, S. C.; Purcaro, M.; Balkam, M.; Robinson, A.; Behabadi, B. F. et al.; Campos, M.; Denk, W.; Seung, H. S.; EyeWirers: Space-time wiring specificity supports direction selectivity in the retina. Nature 509 (7500), pp. 331 - 336 (2014)

Helmstaedter, M.; Briggman, K.; Turaga, S. C.; Jain, V.; Seung, H. S.; Denk, W.: Connectomic reconstruction of the inner plexiform layer in the mouse retina. Nature 500 (7461), pp. 168 - 174 (2013)

Titze, B.; Denk, W.: Automated in-chamber specimen coating for serial block-face electron microscopy. Journal of Microscopy 250 (2), pp. 101 - 110 (2013)

Binding, J.; Mikula, S.; Denk, W.: Low-dosage maximum-a-posteriori focusing and stigmation. Microscopy and Microanalysis 19 (1), pp. 38 - 55 (2013)

Helmchen, F.; Denk, W.; Kerr, J. N.: Miniaturization of two-photon microscopy for imaging in freely moving animals. Cold Spring Harbor Protocols 2013 (10), pp. 904 - 913 (2013)

Mikula, S.; Binding, J.; Denk, W.: Staining and embedding the whole mouse brain for electron microscopy. Nature Methods 9 (12), pp. 1198 - 1201 (2012)

Bargmann, C.; Denk, W.; Graybiel, A.: An interview with...: The Kavli prize winners. Nature Reviews Neuroscience 13 (10), pp. 669 - 673 (2012)

Andres, B.; Koethe, U.; Kroeger, T.; Helmstaedter, M.; Briggman, K.; Denk, W.; Hamprecht, F. A.: 3D segmentation of SBFSEM images of neuropil by a graphical model over supervoxel boundaries. Medical Image Analysis 16 (4), pp. 796 - 805 (2012)

Denk, W.; Briggman, K.; Helmstaedter, M.: Structural neurobiology: Missing link to a mechanistic understanding of neural computation. Nature Reviews Neuroscience 13 (5), pp. 351 - 358 (2012)

Denk, W.; Miesenböck, G.: Neurotechnology: Summa technologiae. Current Opinion in Neurobiology 22 (1), pp. 1 - 2 (2012)

Kleinfeld, D.; Bharioke, A.; Blinder, P.; Bock, D. D.; Briggman, K.; Chklovskii, D. B.; Denk, W.; Helmstaedter, M.; Kaufhold, J. P.; Lee, W. A. et al.; Meyer, H. S.; Micheva, K. D.; Oberlaender, M.; Prohaska, S.; Reid, R. C.; Smith, S. J.; Takemura, S.; Tsai, P. S.; Sakmann, B.: Large-scale automated histology in the pursuit of connectomes. The Journal of Neuroscience 31 (45), pp. 16125 - 16138 (2011)