Publications of Dieter E. Jenne

Hamon, Y.; Legowska, M.; Herve, V.; Dallet-Choisy, S.; Marchand-Adam, S.; Vanderlynden, L.; Demonte, M.; Williams, R.; Scott, C. J.; Si-Tahar, M. et al.; Heuze-Vourc'h, N.; Lalmanach, G.; Jenne, D. E.; Lesner, A.; Gauthier, F.; Korkmaz, B.: Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases. The Journal of Biological Chemistry 291 (16), pp. 8486 - 8499 (2016)

Korkmaz, B.; Lesner, A.; Guarino, C.; Wysocka, M.; Kellenberger, C.; Watier, H.; Specks, U.; Gauthier, F.; Jenne, D. E.: Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease. Pharmacological Reviews 68 (3), pp. 603 - 630 (2016)

Dau, T.; Sarker, R. S. J.; Yildirim, A. O.; Eickelberg, O.; Jenne, D. E.: Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nature Communications 6, 6722 (2015)

Hinkofer, L. C.; Hummel, A. M.; Stone, J. H.; Hoffman, G. S.; Merkel, P. A.; Spiera, E. R. F.; Clair, W. S.; McCune, J. W.; Davis, J. C.; Specks, U. et al.; Jenne, D. E.: Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis. Journal of Autoimmunity 59, pp. 43 - 52 (2015)

Laurent, S. A.; Hoffmann, F. S.; Kuhn, P.-H.; Cheng, Q.; Chu, Y.; Schmidt-Supprian, M.; Hauck, S. M.; Schuh, E.; Krumbholz, M.; Rübsamen, H. et al.; Wanngren, J.; Khademi, M.; Olsson, T.; Alexander, T.; Hiepe, F.; Pfister, H.-W.; Weber, F.; Jenne, D. E.; Wekerle, H.; Hohlfeld, R.; Lichtenthaler, S. F.; Meinl, E.: γ-secretase directly sheds the survival receptor BCMA from plasma cells. Nature Communications 6, 7333 (2015)

Guarino, C.; Legowska, M.; Epinette, C.; Kellenberger, C.; Dallet-Choisy, S.; Sienczyk, M.; Gabant, G.; Cadene, M.; Zoidakis, J.; Vlahou, A. et al.; Wysocka, M.; Marchand-Adam, S.; Jenne, D. E.; Lesner, A.; Gauthier, F.; Korkmaz, B.: New selective peptidyl Di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases. The Journal of Biological Chemistry 289 (46), pp. 31777 - 31791 (2014)

Guyot, N.; Wartelle, J.; Malleret, L.; Todorov, A. A.; Devouassoux, G.; Pacheco, Y.; Jenne, D. E.; Belaaouaj, A.: Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema. American Journal of Pathology 184 (8), pp. 2197 - 2210 (2014)

Jenne, D. E.: Off-target rewards of augmentation therapy with α1-antitrypsin. American Journal of Respiratory and Critical Care Medicine 190 (11), pp. 1203 - 1204 (2014)

Hedberg, C.; Melberg, A.; Kuhl, A.; Jenne, D. E.; Oldfors, A.: Functional characterization of desmin mutant p.P419S Reply [Letter]. European journal of human genetics 21 (6), p. 590 - 590 (2013)

Hinkofer, L. C.; Seidel, S. A. I.; Korkmaz, B.; Silva, F.; Hummel, A. M.; Braun, D.; Jenne, D. E.; Specks, U.: A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism. The Journal of Biological Chemistry 288 (37), pp. 26635 - 26648 (2013)

Mayer, M. C.; Breithaupt, C.; Reindl, M.; Schanda, K.; Rostasy, K.; Berger, T.; Dale, R. C.; Brilot, F.; Olsson, T.; Jenne, D. E. et al.; Proebstel, A.-K.; Dornmair, K.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.: Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of Immunology 191 (7), pp. 3594 - 3604 (2013)

Molnarfi, N.; Schulze-Topphoff, U.; Weber, M. S.; Patarroyo, J. C.; Prod'homme, T.; Varrin-Doyer, M.; Shetty, A.; Linington, C.; Slavin, A. J.; Hidalgo, J. et al.; Jenne, D. E.; Wekerle, H.; Sobel, R. A.; Bernard, C. C. A.; Shlomchik, M. J.; Zamvil, S. S.: MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. Journal of Experimental Medicine 210 (13), pp. 2921 - 2937 (2013)

O'Donoghue, A. J.; Jin, Y.; Knudsen, G. M.; Perera, N. C.; Jenne, D. E.; Murphy, J. E.; Craik, C. S.; Hermiston, T. W.: Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. PLoS One 8 (9), e75141 (2013)

Perera, N. C.; Wiesmueller, K.-H.; Larsen, M. T.; Schacher, B.; Eickholz, P.; Borregaard, N.; Jenne, D. E.: NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. Journal of Immunology 191 (5), pp. 2700 - 2707 (2013)

Hedberg, C.; Melberg, A.; Kuhl, A.; Jenne, D. E.; Oldfors, A.: Autosomal dominant myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7 is caused by a DES mutation. European journal of human genetics 20 (9), pp. 984 - 985 (2012)

Lippok, S.; Seidel, S. A. I.; Duhr, S.; Uhland, K.; Holthoff, H.-P.; Jenne, D. E.; Braun, D.: Direct detection of antibody concentration and affinity in human serum using microscale thermophoresis. Analytical Chemistry 84 (8), pp. 3523 - 3530 (2012)

Mankan, A. K.; Dau, T.; Jenne, D. E.; Hornung, V.: The NLRP3/ASC/Caspase-1 axis regulates IL-1 ss processing in neutrophils. European Journal of Immunology 42 (3), pp. 710 - 715 (2012)

Perera, N. C.; Jenne, D. E.: Perspectives and potential roles for the newly discovered NSP4 in the immune system. Expert Review of Clinical Immunology 8 (6), pp. 501 - 503 (2012)

Perera, N. C.; Schilling, O.; Kittel, H.; Back, W.; Kremmer, E.; Jenne, D. E.: NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proceedings of the National Academy of Sciences of the United States of America 109 (16), pp. 6229 - 6234 (2012)

Croker, B. A.; Lewis, R. S.; Babon, J. J.; Mintern, J. D.; Jenne, D. E.; Metcalf, D.; Zhang, J. G.; Cengia, L. H.; O'Donnell, J. A.; Roberts, A. W.: Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease. Journal of Immunology 186 (2), pp. 1131 - 1139 (2011)