Publications of Dieter E. Jenne

Guarino, C.; Seren, S.; Lemoine, R.; Hummel, A. M.; Margotin, J.-E.; El-Benna, J.; Hoarau, C.; Specks, U.; Jenne, D. E.; Korkmaz, B.: Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils. The Journal of Biological Chemistry 299 (4), 103072 (2023)

Janakiraman, M.; Leliavski, A.; Varadarajulu, J.; Jenne, D. E.; Krishnamoorthy, G.: An engineered Fc fusion protein that targets antigen-specific T cells and autoantibodies mitigates autoimmune disease. Journal of Neuroinflammation 20, 291 (2023)

Spella, M.; Ntaliarda, G.; Skiadas, G.; Lamort, A.-S.; Vreka, M.; Marazioti, A.; Lilis, I.; Bouloukou, E.; Giotopoulou, G. A.; Pepe, M. A. A. et al.; Weiss, S. A. I.; Petrera, A.; Hauck, S. M.; Koch, I.; Lindner, M.; Hatz, R. A.; Behr, J.; Arendt, K. A. M.; Giopanou, I.; Brunn, D.; Savai, R.; Jenne, D. E.; de Chateau, M.; Yull, F. E.; Blackwell, T. S.; Stathopoulos, G. T.: Non-oncogene addiction of KRAS-mutant cancers to IL-1beta via versican and mononuclear IKKbeta. Cancers / Molecular Diversity Preservation International (MDPI) 15 (6), 1866 (2023)

Ebert, M.; Jerke, U.; Eulenberg-Gustavus, C.; Kling, L.; Jenne, D. E.; Kirchner, M.; Mertins, P.; Bieringer, M.; Elitok, S.; Eckardt, K.-U. et al.; Schreiber, A.; Salama, A. D.; Kettritz, R.: Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation. The Journal of Clinical Investigation 132 (23), e160089 (2022)

Kessler, N.; Viehmann, S. F.; Krollmann, C.; Mai, K.; Kirschner, K. M.; Luksch, H.; Kotagiri, P.; Böhner, A. M. C.; Huugen, D.; de Oliveira Mann, C. C. et al.; Otten, S.; Weiss, S. A. I.; Zillinger, T.; Dobrikova, K.; Jenne, D. E.; Behrendt, R.; Ablasser, A.; Bartok, E.; Hartmann, G.; Hopfner, K.-P.; Lyons, P. A.; Boor, P.; Rösen-Wolff, A.; Teichmann, L. L.; Heeringa, P.; Kurts, C.; Garbi, N.: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing. The Journal of experimental medicine 219 (10), e20220759 (2022)

Morrone, C.; Smirnova, N. F.; Jeridi, A.; Kneidinger, N.; Hollauer, C.; Schupp, J. C.; Kaminski, N.; Jenne, D. E.; Eickelberg, O.; Yildirim, A. O.: Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome. European Respiratory Journal 57 (5), 2001416 (2021)

Schoeps, B.; Eckfeld, C.; Prokopchuk, O.; Boettcher, J.; Haeussler, D.; Steiger, K.; Demir, I. E.; Knolle, P.; Soehnlein, O.; Jenne, D. E. et al.; Hermann, C. D.; Krueger, A.: TIMP1 triggers neutrophil extracellular trap formation in pancreatic cancer. Cancer Research 81 (13), pp. 3568 - 3579 (2021)

Seren, S.; Derian, L.; Keles, I.; Guillon, A.; Lesner, A.; Gonzalez, L.; Baranek, T.; Si-Tahar, M.; Marchand-Adam, S.; Jenne, D. E. et al.; Paget, C.; Jouan, Y.; Korkmaz, B.: Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia. European Respiratory Journal 57 (4), 2003755 (2021)

Korkmaz, B.; Lesner, A.; Marchand-Adam, S.; Moss, C.; Jenne, D. E.: Lung protection by cathepsin C inhibition: A new hope for COVID-19 and ARDS? Journal of Medicinal Chemistry 63 (22), pp. 13258 - 13265 (2020)

Fernandez, I. M.; Macrini, C.; Krumbholz, M.; Hensbergen, P. J.; Ederveen, A. L. H.; Winklmeier, S.; Vural, A.; Kurne, A.; Jenne, D. E.; Kamp, F. et al.; Gerdes, L. A.; Hohlfeld, R.; Wuhrer, M.; Kümpfel, T.; Meinl, E.: The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients. Frontiers in immunology 10, 1189 (2019)

Korkmaz, B.; Lesner, A.; Wysocka, M.; Gieldon, A.; Hakansson, M.; Gauthier, F.; Logan, D. T.; Jenne, D. E.; Lauritzen, C.; Pedersen, J.: Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochemical Pharmacology 164, pp. 349 - 367 (2019)

Lamort, A.-S.; Hamon, Y.; Czaplewski, C.; Gieldon, A.; Seren, S.; Coquet, L.; Lecaille, F.; Lesner, A.; Lalmanach, G.; Gauthier, F. et al.; Jenne, D. E.; Korkmaz, B.: Processing and maturation of cathepsin C zymogen: A biochemical and molecular modeling analysis. International Journal of Molecular Sciences 20 (19), 4747 (2019)

Rehm, S. R. T.; Smirnova, N. F.; Morrone, C.; Goetzfried, J.; Feuchtinger, A.; Pedersen, J.; Korkmaz, B.; Yildirim, A. O.; Jenne, D. E.: Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. Scientific Reports 9, 9925 (2019)

Goetzfried, J.; Smirnova, N. F.; Morrone, C.; Korkmaz, B.; Yildirim, A. O.; Eickelberg, O.; Jenne, D. E.: Preservation with α1-antitrypsin improves primary graft function of murine lung transplants. The Journal of Heart and Lung Transplantation 37 (8), pp. 1021 - 1028 (2018)

Guarino, C.; Gruba, N.; Grzywa, R.; Dyguda-Kazimierowicz, E.; Hamon, Y.; Legowska, M.; Skorenski, M.; Dallet-Choisy, S.; Marchand-Adam, S.; Kellenberger, C. et al.; Jenne, D. E.; Sienczyk, M.; Lesner, A.; Gauthier, F.; Korkmaz, B.: Exploiting the S4-S5 specificity of human neutrophil proteinase 3 to improve the potency of deptidyl Di(chlorophenyl)-phosphonate ester inhibitors: A kinetic and molecular modeling analysis. Journal of Medicinal Chemistry 61 (5), pp. 1858 - 1870 (2018)

Seren, S.; Abouzaid, M. R.; Eulenberg-Gustavus, C.; Hirschfeld, J.; Soliman, H. N.; Jerke, U.; N'Guessan, K.; Dallet-Choisy, S.; Lesner, A.; Lauritzen, C. et al.; Schacher, B.; Eickholz, P.; Nagy, N.; Szell, M.; Croix, C.; Viaud-Massuard, M.-C.; Aldosari, A. A. F.; Ragunatha, S.; Mostafa, M. I.; Giampieri, F.; Battino, M.; Cornillier, H.; Lorette, G.; Stephan, J.-L.; Goizet, C.; Pedersen, J.; Gauthier, F.; Jenne, D. E.; Marchand-Adam, S.; Chapple, I. L.; Kettritz, R.; Korkmaz, B.: Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis. The Journal of Biological Chemistry 293 (32), pp. 12415 - 12428 (2018)

Spadaro, M.; Winklmeier, S.; Beltran, E.; Macrini, C.; Hoeftberger, R.; Schuh, E.; Thaler, F. S.; Gerdes, L. A.; Laurent, S.; Gerhards, R. et al.; Braendle, S.; Dornmair, K.; Breithaupt, C.; Krumbholz, M.; Moser, M.; Krishnamoorthy, G.; Kamp, F.; Jenne, D. E.; Hohlfeld, R.; Kuempfel, T.; Lassmann, H.; Kawakami, N.; Meinl, E.: Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. Annals of Neurology 84 (2), pp. 315 - 328 (2018)

Guarino, C.; Hamon, Y.; Croix, C.; Lamort, A.-S.; Dallet-Choisy, S.; Marchand-Adam, S.; Lesner, A.; Baranek, T.; Viaud-Massuard, M.-C.; Lauritzen, C. et al.; Pedersen, J.; Heuze-Vourc'h, N.; Si-Tahar, M.; Firatli, E.; Jenne, D. E.; Gauthier, F.; Horwitz, M. S.; Borregaard, N.; Korkmaz, B.: Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases. Biochemical Pharmacology 131, pp. 52 - 67 (2017)

Dau, T.; Edeleva, E. V.; Seidel, S. A. I.; Stockley, R. A.; Braun, D.; Jenne, D. E.: Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis. Scientific Reports 6, 35413 (2016)

Hamon, Y.; Legowska, M.; Fergelot, P.; Dallet-Choisy, S.; Newell, L.; Vanderlynden, L.; Valeshabad, A. K.; Acrich, K.; Kord, H.; Charalampos, T. et al.; Morice-Picard, F.; Surplice, I.; Zoidakis, J.; David, K.; Vlahou, A.; Ragunatha, S.; Nagy, N.; Farkas, K.; Szell, M.; Goizet, C.; Schacher, B.; Battino, M.; Aldosari, A. A. F.; Wang, X.; Liu, Y.; Marchand-Adam, S.; Lesner, A.; Kara, E.; Korkmaz-Icoez, S.; Moss, C.; Eickholz, P.; Taieb, A.; Kavukcu, S.; Jenne, D. E.; Gauthier, F.; Korkmaz, B.: Analysis of urinary cathepsin C for diagnosing Papillon-Lefevre syndrome. The FEBS Journal 283 (3), pp. 498 - 509 (2016)