Publications of Rüdiger Klein

Schimmang, T.; AlvarezBolado, G.; Minichiello, L.; Vazquez, E.; Giraldez, F.; Klein, R.; Represa, J.: Survival of inner ear sensory neurons in trk mutant mice. Mechanisms of Development 64 (1-2), pp. 77 - 85 (1997)

Schober, A.; Minichiello, L.; Keller, M.; Huber, K.; Layer, P. G.; Roig-López, J. L.; Garcı́a-Arrarás, J. E.; Klein, R.; Unsicker, K.: Reduced acetylcholinesterase (AChE) activity in adrenal medulla and loss of sympathetic preganglionic neurons in TrkA-deficient, but not TrkB-deficient, mice. The Journal of Neuroscience 17 (3), pp. 891 - 903 (1997)

Brambilla, R.; Brückner, K.; Orioli, D.; Bergemann, A. D.; Flanagan, J. G.; Klein, R.: Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Molecular and Cellular Neuroscience 8 (2-3), pp. 199 - 209 (1996)

Henkemeyer, M.; Orioli, D.; Henderson, J. T.; Saxton, T. M.; Roder, J.; Pawson, T.; Klein, R.: Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86 (1), pp. 35 - 46 (1996)

Maina, F.; Casagranda, F.; Audero, E.; Simeone, A.; Comoglio, P. M.; Klein, R.; Ponzetto, C.: Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development. Cell 87 (3), pp. 531 - 542 (1996)

Minichiello, L.; Klein, R.: TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes and Development 10 (22), pp. 2849 - 2858 (1996)

Orioli, D.; Henkemeyer, M.; Lempe, G.; Klein, R.; Pawson, T.: Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. The EMBO Journal 15 (22), pp. 6035 - 6049 (1996)

Pinon, L. G. P.; Minichiello, L.; Klein, R.; Davies, A. M.: Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development 122 (10), pp. 3255 - 3261 (1996)

Minichiello, L.; Piehl, F.; Vazquez, E.; Schimmang, T.; Hokfelt, T.; Represa, J.; Klein, R.: Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development 121 (12), pp. 4067 - 4075 (1995)

Gassmann, M.; Casagranda, F.; Orioli, D.; Simon, H.; Lai, C.; Klein, R.; Lemke, G.: Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378 (6555), pp. 390 - 394 (1995)

Schimmang, T.; Minichiello, L.; Vazquez, E.; Jose, I. S.; Giraldez, F.; Klein, R.; Represa, J.: Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets. Development 121 (10), pp. 3381 - 3391 (1995)

Davies, A. M.; Minichiello, L.; Klein, R.: Developmental changes in NT3 signaling via TrkA and TrkB in embryonic neurons. The EMBO Journal 14 (18), pp. 4482 - 4489 (1995)

Brambilla, R.; Schnapp, A.; Casagranda, F.; Labrador, J. P.; Bergemann, A. D.; Flanagan, J. G.; Pasquale, E. B.; Klein, R.: Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. The EMBO Journal 14 (13), pp. 3116 - 3126 (1995)

Tannahill, L.; Klein, R.; Schachner, M.: The neurotrophin receptors TrkA and TrkB are inhibitory for neurite outgrowth. European Journal of Neuroscience: European Neuroscience Association 7 (6), pp. 1424 - 1428 (1995)

Bergemann, A. D.; Cheng, H. J.; Brambilla, R.; Klein, R.; Flanagan, J. G.: ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Molecular and Cellular Biology (Washington, DC) 15 (9), pp. 4921 - 4929 (1995)

Brambilla, R.; Klein, R.: Telling axons where to grow: A role for Eph receptor tyrosine kinases in guidance. Molecular and Cellular Neuroscience 6 (6), pp. 487 - 495 (1995)

Klein, R.: Role of neurotrophins in mouse neuronal development. The FASEB Journal 8 (10), pp. 738 - 744 (1994)

Klein, R.; Silossantiago, I.; Smeyne, R. J.; Lira, S. A.; Brambilla, R.; Bryant, S.; Zhang, L.; Snider, W. D.; Barbacid, M.: Disruption of the neurotrophin-3 receptor gene trkC eliminates Ia muscle afferents and results in abnormal movements. Nature 368 (6468), pp. 249 - 251 (1994)

Smeyne, R. J.; Klein, R.; Schnapp, A.; Long, L. K.; Bryant, S.; Lewin, A.; Lira, S. A.; Barbacid, M.: Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368 (6468), pp. 246 - 249 (1994)

Klein, R.; Smeyne, R. J.; Wurst, W.; Long, L. K.; Auerbach, B. A.; Joyner, A. L.; Barbacid, M.: Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75 (1), pp. 113 - 122 (1993)