Publications of R. Klein

Grunwald, I. C.; Klein, R.: Axon guidance: Receptor complexes and signaling mechanisms. Current Opinion in Neurobiology 12 (3), pp. 250 - 259 (2002)

Palmer, A.; Zimmer, M.; Erdmann, K. S.; Eulenburg, V.; Porthin, A.; Heumann, R.; Deutsch, U.; Klein, R.: EphrinB phosphorylation and reverse signaling: Regulation by Src kinases and PTP-BL phosphatase. Molecular Cell 9 (4), pp. 725 - 737 (2002)

Postigo, A.; Calella, A. M.; Fritzsch, B.; Knipper, M.; Katz, D.; Eilers, A.; Schimmang, T.; Lewin, G. R.; Klein, R.; Minichiello, L.: Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons. Genes and Development 16 (5), pp. 633 - 645 (2002)

Ikeda, K.; Wang, L.H.; Torres, R.; Zhao, H.; Olaso, E.; Eng Francis, J.; Labrador, P.; Klein, R.; Lovett, D.; Yancopoulos, G.D. et al.; Friedman, S.L.; Lin, H.C.: Discoidin Domain Receptor 2 (DDR2) interacts with Src and Shc following its activation by Type I collagen. The Journal of Biological Chemistry 277, pp. 19206 - 19212 (2002)

Klein, R.: Novel effector function for an old receptor. Nature Cell Biology 4 (1), pp. E11 - E12 (2002)

Olaso, E.; Labrador, J.P.; Wang, L.; Ikeda, K.; Eng, F.J.; Klein, R.; Lovett, D.H.; Lin, H.C.; Friedman, S.L.: Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. The Journal of Biological Chemistry 277, pp. 3606 - 3613 (2002)

Vyssotski, A.L.; Dell'Omo, G.; Poletaeva, I.I.; Vyssotski, D.L.; Minichiello, L.; Klein, R.; Wolfer, D.P.; Lipp, H.-P.: Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: Mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility. Hippocampus 12 (1), pp. 27 - 38 (2002)

Zhang, S.Q.; Tsiaras, B.; Araki, T.; Wen, G.; Minichiello, L.; Klein, R.; Neel, B.G.: Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2. Molecular and Cellular Biology (Washington, DC) 22, pp. 4062 - 4072 (2002)

Adams, R. H.; Diella, F.; Hennig, S.; Helmbacher, F.; Deutsch, U.; Klein, R.: The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell 104 (1), pp. 57 - 69 (2001)

Graus-Porta, D.; Blaess, S.; Senften, M.; Littlewood-Evans, A.; Damsky, C.; Huang, Z.; Orban, P.; Klein, R.; Schittny, J. C.; Muller, U.: β1-Class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex. Neuron 31 (3), pp. 367 - 379 (2001)

Grunwald, I. C.; Korte, M.; Wolfer, D.; Wilkinson, G. A.; Unsicker, K.; Lipp, H. P.; Bonhoeffer, T.; Klein, R.: Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron 32 (6), pp. 1027 - 1040 (2001)

Klein, R.: Excitatory Eph receptors and adhesive ephrin ligands. Current Opinion in Cell Biology 13 (2), pp. 196 - 203 (2001)

Kullander, K.; Croll, S. D.; Zimmer, M.; Pan, L.; McClain, J.; Hughes, V.; Zabski, S.; DeChiara, T. M.; Klein, R.; Yancopoulos, G. D. et al.; Gale, N. W.: Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. Genes and Development 15 (7), pp. 877 - 888 (2001)

Kullander, K.; Mather, N. K.; Diella, F.; Dottori, M.; Boyd, A. W.; Klein, R.: Kinase-dependent and kinase-independent functions of EphA4 receptors in major axon tract formation in vivo. Neuron 29 (1), pp. 73 - 84 (2001)

Labrador, J. P.; Azcoitia, V.; Tuckermann, J.; Lin, C.; Olaso, E.; Manes, S.; Brückner, K.; Goergen, J. L.; Lemke, G.; Yancopoulos, G. et al.; Angel, P.; Martinez, C.; Klein, R.: The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Reports 2 (5), pp. 446 - 452 (2001)

Maina, F.; Pante, G.; Helmbacher, F.; Andres, R.; Porthin, A.; Davies, A. M.; Ponzetto, C.; Klein, R.: Coupling met to specific pathways results in distinct developmental outcomes. Molecular Cell 7 (6), pp. 1293 - 1306 (2001)

Adams, R. H.; Klein, R.: Eph receptors and ephrin ligands: Essential mediators of vascular development. Trends in Cardiovascular Medicine 10 (5), pp. 183 - 188 (2000)

Adams, R. H.; Porras, A.; Alonso, G.; Jones, M.; Vintersten, K.; Panelli, S.; Valladares, A.; Perez, L.; Klein, R.; Nebreda, A. R.: Essential role of p38α MAP kinase in placental but not embryonic cardiovascular development. Molecular Cell 6 (1), pp. 109 - 116 (2000)

Brüning, J. C.; Gautam, D.; Burks, D. J.; Gillette, J.; Schubert, M.; Orban, P. C.; Klein, R.; Krone, W.; Müller-Wieland, D.; Kahn, C. R.: Role of brain insulin receptor in control of body weight and reproduction. Science 289 (5487), pp. 2122 - 2125 (2000)

Caton, A.; Hacker, A.; Naeem, A.; Livet, J.; Maina, F.; Bladt, F.; Klein, R.; Birchmeier, C.; Guthrie, S.: The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons. Development 127 (8), pp. 1751 - 1766 (2000)