Publications of Reinhard Hohlfeld

Chevrel, G.; Hohlfeld, R.; Sendtner, M.: The role of neurotrophins in muscle under physiological and pathological conditions. Muscle & Nerve 33 (4), pp. 462 - 476 (2006)

Gold, R.; Hartung, H. P.; Hohlfeld, R.: Monoclonal antibodies improve therapy of relapsing multiple sclerosis. Molecular basis and clinical results of anti-VLA4 (natalizumab) therapy. Deutsche Medizinische Wochenschrift 131 (1-2), pp. 31 - 34 (2006)

Hoffmann, L. A.; Kümpfel, T.; Heer, I.; Hohlfeld, R.: Pregnancy and immunomodulatory therapy in multiple sclerosis patients. Nervenarzt 6, pp. 663, 666, 670 - 664, 668 (2006)

Hohlfeld, R.; Kerschensteiner, M.; Stadelmann, C.; Lassmann, H.; Wekerle, H.: The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis. Neurological Sciences 27, pp. S1 - S7 (2006)

Krumbholz, M.; Theil, D.; Cepok, S.; Hemmer, B.; Kivisakk, P.; Ransohoff, R. M.; Hofbauer, M.; Farina, C.; Derfuss, T.; Hartle, C. et al.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 129, pp. 200 - 211 (2006)

Martin, R.; Bielekova, B.; Hohlfeld, R.; Utz, U.: Biomarkers in multiple sclerosis. Disease Markers 22 (4), pp. 183 - 185 (2006)

Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in inflammatory central nervous system - Reply. Annals of Neurology 60 (4), p. 487 - 487 (2006)

Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production, and therapeutic modulation. Annals of Neurology 59 (6), pp. 880 - 892 (2006)

Seitz, S.; Schneider, C. K.; Malotka, J.; Nong, X.; Engel, A. G.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: Reconstitution of paired T cell receptor α- and β-chains from microdissected single cells of human inflammatory tissues. Proceedings of the National Academy of Sciences of the United States of America 103 (32), pp. 12057 - 12062 (2006)

Wiendl, H.; Kieseier, B. C.; Gold, R.; Hohlfeld, R.; Bendszus, M.; Hartung, H. P.: Revision of McDonald's new diagnostic criteria for multiple sclerosis. Nervenarzt 10, pp. 1235 - 1245 (2006)

Derfuss, T.; Hohlfeld, R.; Meinl, E.: Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response. Journal of Neurology 252 (8), pp. 968 - 971 (2005)

Farina, C.; Weber, M. S.; Meinl, E.; Wekerle, H.; Hohlfeld, R.: Glatiramer acetate in multiple sclerosis: Update on potential mechanisms of action. Lancet Neurology 4 (9), pp. 567 - 575 (2005)

Hohlfeld, R.; Wekerle, H.: Drug insight: Using monoclonal antibodies to treat multiple sclerosis. Nature Clinical Practice Neurology 1, pp. 34 - 44 (2005)

Krumbholz, M.; Theil, D.; Derfuss, T.; Rosenwald, A.; Schrader, F.; Monoranu, C. M.; Kalled, S. L.; Hess, D. M.; Serafini, B.; Aloisi, F. et al.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), pp. 195 - 200 (2005)

Vargas-Leal, V.; Bruno, R.; Derfuss, T.; Krumbholz, M.; Hohlfeld, R.; Meinl, E.: Expression and function of glial cell line-derived neurotrophic factor (GDNF) family ligands and their receptors on human immune cells. Journal of Immunology 175 (4), pp. 2301 - 2308 (2005)

Wiendl, H.; Hohlfeld, R.; Kieseier, B. C.: Immunobiology of muscle: Advances in understanding an immunological microenvironment. Trends in Immunology 26, pp. 373 - 380 (2005)

Ziemssen, T.; Kümpfel, T.; Schneider, H.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Secretion of brain-derived neurotrophic factor by glatiramer acetate-reactive T-helper cell lines: Implications for multiple sclerosis therapy. Journal of the Neurological Sciences 233 (1-2), pp. 109 - 112 (2005)

Clanet, M.; Kappos, L.; Hartung, H. P.; Hohlfeld, R.; The European IFNβ-1a Dose Comparison Study Investigators: Interferon β-1a in relapsing multiple sclerosis: Four-year extension of the European IFNβ-1a Dose Comparison Study. Multiple Sclerosis Journal 10, pp. 139 - 144 (2004)

Dornmair, K.; Schneider, C. K.; Malotka, J.; Dechant, G.; Wiendl, H.; Hohlfeld, R.: Antigen recognition properties of a V gamma LW delta 2-T-cell receptor from a rare variant of polymyositis. Journal of Neuroimmunology 152 (1-2), pp. 168 - 175 (2004)

Farina, C.; Theil, D.; Semlinger, B.; Hohlfeld, R.; Meinl, E.: Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. International Immunology 16 (6), pp. 799 - 809 (2004)