Publications of Hartmut Wekerle

Wekerle, H.: Vaccination and narcolepsy: Immune link found? Science translational medicine: Integrating medicine and science 7 (294), 294fs27 (2015)

Wekerle, H.: Nature plus Nurture: The triggering of multiple sclerosis. Swiss Medical Weekly 145, w14189 (2015)

Ben-Nun, A.; Kaushansky, N.; Kawakami, N.; Krishnamoorthy, G.; Berer, K.; Liblau, R.; Hohlfeld, R.; Wekerle, H.: From classic to spontaneous and humanized models of multiple sclerosis: Impact on understanding pathogenesis and drug development. Journal of Autoimmunity 54, pp. 33 - 50 (2014)

Koutrolos, M.; Berer, K.; Kawakami, N.; Wekerle, H.; Krishnamoorthy, G.: Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS. Acta Neuropathologica Communications 2, 163 (2014)

Mohan, H.; Friese, A.; Albrecht, S.; Krumbholz, M.; Elliott, C. L.; Arthur, A.; Menon, R.; Farina, C.; Junker, A.; Stadelmann, C. et al.; Barnett, S. C.; Huitinga, I.; Wekerle, H.; Hohlfeld, R.; Lassmann, H.; Kuhlmann, T.; Linington, C.; Meinl, E.: Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. Acta Neuropathologica Communications 2, 168 (2014)

Mayer, M. C.; Breithaupt, C.; Reindl, M.; Schanda, K.; Rostasy, K.; Berger, T.; Dale, R. C.; Brilot, F.; Olsson, T.; Jenne, D. E. et al.; Proebstel, A.-K.; Dornmair, K.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.: Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of Immunology 191 (7), pp. 3594 - 3604 (2013)

Molnarfi, N.; Schulze-Topphoff, U.; Weber, M. S.; Patarroyo, J. C.; Prod'homme, T.; Varrin-Doyer, M.; Shetty, A.; Linington, C.; Slavin, A. J.; Hidalgo, J. et al.; Jenne, D. E.; Wekerle, H.; Sobel, R. A.; Bernard, C. C. A.; Shlomchik, M. J.; Zamvil, S. S.: MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. Journal of Experimental Medicine 210 (13), pp. 2921 - 2937 (2013)

Mues, M.; Bartholomäus, I.; Thestrup, T.; Griesbeck, O.; Wekerle, H.; Kawakami, N.; Krishnamoorthy, G.: Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator. Nature Medicine 19 (6), pp. 778 - 783 (2013)

Neumann, H.; Wekerle, H.: Brain microglia: Watchdogs with pedigree. Nature Neuroscience 16 (3), pp. 253 - 255 (2013)

Pesic, M.; Bartholomäus, I.; Kyratsous, N. I.; Heissmeyer, V.; Wekerle, H.; Kawakami, N.: 2-photon imaging of phagocyte-mediated T cell activation in the CNS. The Journal of Clinical Investigation 123 (3), pp. 1192 - 1201 (2013)

Pohl, M.; Kawakami, N.; Kitic, M.; Bauer, J.; Martins, R.; Fischer, M.-T.; Machado-Santos, J.; Mader, S.; Ellwart, J. W.; Misu, T. et al.; Fujihara, K.; Wekerle, H.; Reindl, M.; Lassmann, H.; Bradl, M.: T cell-activation in neuromyelitis optica lesions plays a role in their formation. Acta Neuropathologica Communications 1, 85 (2013)

Wekerle, H.: Tissue hypoxia in autoimmune brain disease: A Columbian discovery? Annals of Neurology 74 (6), pp. 765 - 767 (2013)

Wekerle, H.; Berer, K.; Krishnamoorthy, G.: Remote control - triggering of brain autoimmune disease in the gut. Current Opinion in Immunology 25 (6), pp. 683 - 689 (2013)

Wekerle, H.; Meinl, E.: Multiple sclerosis: An old drug plays a new trick. Nature 502 (7471), pp. 314 - 315 (2013)

Hohlfeld, R.; Wekerle, H.: β-Amyloid: Enemy or remedy? Science translational medicine: Integrating medicine and science 4 (145), 145fs24 (2012)

Odoardi, F.; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D.; Heckelsmiller, K.; Nietfeld, W.; Ellwart, J.; Klinkert, W. E. F. et al.; Lottaz, C.; Nosov, M.; Brinkmann, V.; Spang, R.; Lehrach, H.; Vingron, M.; Wekerle, H.; Fluegel-Koch, C.; Fluegel, A.: T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), pp. 675 - 679 (2012)

Siewert, K.; Malotka, J.; Kawakami, N.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: Unbiased identification of target antigens of CD8(+) T cells with combinatorial libraries coding for short peptides. Nature Medicine 18 (5), pp. 824 - 828 (2012)

Wekerle, H.; Fluegel, A.; Fugger, L.; Schett, G.; Serreze, D.: Autoimmunity's next top models. Nature Medicine 18 (1), pp. 66 - 70 (2012)

Wekerle, H.; Krishnamoorthy, G.: Brain Autoimmunity: The CD8 Question(s). Immunity 37 (1), pp. 8 - 10 (2012)

Berer, K.; Mues, M.; Koutrolos, M.; Al Rasbi, Z.; Boziki, M.; Johner, C.; Wekerle, H.; Krishnamoorthy, G.: Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479 (7374), pp. 538 - 541 (2011)