Publications of Hartmut Wekerle

Berer, K.; Wekerle, H.; Krishnamoorthy, G.: B cells in spontaneous autoimmune diseases of the central nervous system. Molecular Immunology 48 (11), pp. 1332 - 1337 (2011)

Obermeier, B.; Lovato, L.; Bruck, W.; Forne, I.; Imhof, A.; Mentele, R.; Lottspeich, F.; Turk, K. W.; Willis, S. N.; Wekerle, H. et al.; Hohlfeld, R.; Hafler, D. A.; O'Connor, K. C.; Dornmair, K.: Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. Journal of Neuroimmunology 233 (1-2), pp. 245 - 248 (2011)

Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), pp. 580 - 588 (2011)

Mohan, H.; Krumbholz, M.; Sharma, R.; Eisele, S.; Junker, A.; Sixt, M.; Newcombe, J.; Wekerle, H.; Hohlfeld, R.; Lassmann, H. et al.; Meinl, E.: Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells. Brain Pathology 20 (5), pp. 966 - 975 (2010)

Wekerle, H.; Sun, D. M.: Fragile privileges: Autoimmunity in brain and eye. Acta Pharmacologica Sinica 31 (9), pp. 1141 - 1148 (2010)

Wekerle, H.; Hohlfeld, R.: Beneficial brain autoimmunity? Brain 133, pp. 2182 - 2184 (2010)

Wekerle, H.; Hohlfeld, R.: Molecular oracles for multiple sclerosis therapy. Nature Medicine 16 (4), pp. 376 - 377 (2010)

Wekerle, H.; Hohlfeld, R.: Zero Tolerance (to Acetylcholine Receptor) and Ways to Overcome It. Annals of Neurology 67 (4), pp. 422 - 424 (2010)

Domingues, H. S.; Mues, M.; Lassmann, H.; Wekerle, H.; Krishnamoorthy, G.: Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. PLoS One 5 (11), e15531 (2010)

Junker, A.; Krumbholz, M.; Eisele, S.; Mohan, H.; Augstein, F.; Bittner, R.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 132, pp. 3342 - 3352 (2009)

Bartholomäus, I.; Kawakami, N.; Odoardi, F.; Schläger, C.; Miljkovic, D.; Ellwart, J. W.; Klinkert, W. E. F.; Flügel-Koch, C.; Issekutz, T. B.; Wekerle, H. et al.; Flügel, A.: Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature 462 (7269), pp. 94 - 98 (2009)

Krishnamoorthy, G.; Wekerle, H.: EAE: An immunologist's magic eye. European Journal of Immunology 39 (8), pp. 2031 - 2035 (2009)

Pöllinger, B.; Krishnamoorthy, G.; Berer, K.; Lassmann, H.; Bösl, M. R.; Dunn, R.; Domingues, H. S.; Holz, A.; Kurschus, F. C.; Wekerle, H.: Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells. Journal of Experimental Medicine 206 (6), pp. 1303 - 1316 (2009)

Krishnamoorthy, G.; Saxena, A.; Mars, L. T.; Domingues, H. S.; Ben-Nun, A.; Lassmann, H.; Dornmair, K.; Mentele, R.; Kurschus, F. C.; Liblau, R. S. et al.; Wekerle, H.: Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature Medicine 15 (6), pp. 626 - 632 (2009)

Derfuss, T.; Parikh, K.; Velhin, S.; Braun, M.; Mathey, E.; Krumbholz, M.; Kümpfel, T.; Moldenhauer, A.; Rader, C.; Sonderegger, P. et al.; Pöllmann, W.; Tiefenthaller, C.; Bauer, J.; Lassmann, H.; Wekerle, H.; Karagogeos, D.; Hohlfeld, R.; Linington, C.; Meinl, E.: Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America 106 (20), pp. 8302 - 8307 (2009)

Bauer, M.; Brakebusch, C.; Coisne, C.; Sixt, M.; Wekerle, H.; Engelhardt, B.; Fässler, R.: β1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 106 (6), pp. 1920 - 1925 (2009)

Hohlfeld, R.; Wekerle, H.: Reflections on the "intrathymic pathogenesis" of myasthenia gravis. Journal of Neuroimmunology 201-202, pp. 21 - 27 (2008)

Obermeier, B.; Malotka, J.; Kellermann, J.; Kümpfel, T.; Wekerle, H.; Lottspeich, F.; Mentele, R.; Hohlfeld, R.; Dornmair, K.: Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis. Nature Medicine 14 (6), pp. 688 - 693 (2008)

Grundtner, R.; Dornmair, K.; Dahm, R.; Flügel, A.; Kawakami, N.; Zeitelhofer, M.; Schoderboeck, L.; Nosov, M.; Selzer, E.; Willheim, M. et al.; Kiebler, M.; Wekerle, H.; Lassmann, H.; Bradl, M.: Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Neurobiology of Disease 28 (3), pp. 261 - 275 (2007)

Odoardi, F.; Kawakami, N.; Klinkert, W. E. F.; Wekerle, H.; Flügel, A.: Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease. Proceedings of the National Academy of Sciences of the United States of America 104 (47), pp. 18625 - 18630 (2007)